Other intestinal ion channels may also be treated, including the calcium-activated chloride channel CaCC , which has been implicated in other types of infection. One benefit of these inhibitors is that because they are active on the intestinal luminal surface and not necessarily absorbed into the body, they may have an inherently favorable toxicology profile.
Similarly, NIAID grantees at Dartmouth Medical School are studying a major transcriptional regulator for cholera toxin expression and its possible relationship to the berry-bearing plant sea buckthorn.
Further research into the molecular basis of microbial pathogenesis is leading to new discoveries explaining how these herbal and traditional medicines work.
Organization History. Visitor Information Contact Us. Cholera Treatment and Prevention. A man being treated for cholera. Sea buckthorn berries from Russia. Content last reviewed on June 24, Cholera patients do not typically become carriers of the cholera bacteria after they recover, but they get sick if exposed again.
Skip directly to site content Skip directly to page options Skip directly to A-Z link. Cholera - Vibrio cholerae infection. Section Navigation. Facebook Twitter LinkedIn Syndicate. Illness and Symptoms. Minus Related Pages. A physician checking a patient for dehydration.
Person washing hands over a bucket of water. Cholera infection is often mild or without symptoms, but can be severe. It usually takes days for symptoms to appear after a person ingests cholera bacteria, but the time can range from a few hours to 5 days. Persons living in places with unsafe drinking water, poor sanitation, and inadequate hygiene are at the highest risk for cholera. If you think you or a member of your family might have cholera, seek medical attention immediately.
Dehydration can be rapid so fluid replacement is essential. If you have oral rehydration solution ORS , start taking it immediately; it can save a life. Continue to drink ORS at home and while traveling to get medical treatment. If an infant has watery diarrhea, continue breastfeeding.
To test for cholera, doctors must take a stool sample or a rectal swab and send it to a laboratory to look for the cholera bacteria. Cholera can be simply and successfully treated by immediate replacement of the fluid and salts lost through diarrhea. Patients can be treated with oral rehydration solution ORS , a prepackaged mixture of sugar and salts that is mixed with 1 liter of water and drunk in large amounts.
This solution is used throughout the world to treat diarrhea. Severe cases also require intravenous fluid replacement. Antibiotics shorten the course and diminish the severity of the illness, but they are not as important as rehydration.
Persons who develop severe diarrhea and vomiting in countries where cholera occurs should seek medical attention promptly. The disease is not likely to spread directly from one person to another; therefore, casual contact with an infected person is not a risk factor for becoming ill.
Be aware of whether cholera cases have recently occurred in an area you plan to visit. However, the risk for cholera is very low for people visiting areas with epidemic cholera when simple prevention steps are taken. All visitors or residents in areas where cholera is occurring or has occurred should follow recommendations to prevent getting sick:.
Skip directly to site content Skip directly to page options Skip directly to A-Z link. Cholera - Vibrio cholerae infection.
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